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Nulea M504 Wired Vertical Mouse, USB Optical Ergonomic Mouse Wired with 4 Adjustable DPI, 11 RGB Backlight Modes, Compatible for Laptop, PC, Desktop, Mac, Black
Nulea

Nulea M504 Wired Vertical Mouse

Bottom line: The Nulea M504 Wired Vertical Mouse: 57-degree vertical grip keeps the forearm neutral instead of pronated; main trade-off: forward and backward thumb buttons do not work under Mac OS.

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By , Founder & Editor-in-Chief · Listing data updated

Mike Perry — Hardware researcher since 2014. For keyboards, mice, headsets and other PC peripherals, synthesises manufacturer specs and independent reviews rather than first-hand lab testing. Core beat: GPU performance across gaming, rendering, and local-LLM inference.

Pros & Cons

Pros

  • ✓ 57-degree vertical grip keeps the forearm neutral instead of pronated
  • ✓ Four DPI steps: 800, 1200, 2400, 3200, switched on the mouse
  • ✓ Plug and play over USB 2.0, no driver install on Windows or Mac
  • ✓ 11 RGB backlight modes outlining the shell, adjustable to taste

Cons

  • ✗ Forward and backward thumb buttons do not work under Mac OS
  • ✗ No buttons are programmable, so no custom macros or remapping
  • ✗ Wired only: the 1.8m USB cable limits desk placement
  • ✗ Nulea says the vertical grip needs a few days of adjustment

Manufacturer description

The Nulea M504 wired vertical mouse tilts your hand to a 57-degree grip so your forearm stays in a neutral position instead of pronated flat against the desk. That angle is the whole point: it takes the twist out of your wrist during long sessions of browsing, spreadsheet work, or design edits. You get four DPI levels on a dedicated switch, stepping from 800 for precise cursor work up to 1200, 2400, and 3200 for fast movement across large or multi-monitor setups. Setup is plug and play over USB 2.0 with a 1.8m cable, so there are no drivers to install on Laptop, PC, Desktop, or Mac. Eleven…

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SpecPicks Verdict

SpecPicks scored Nulea M504 Wired Vertical Mouse using a rating × review-volume × price-fit model applied to published specs and reviews across the gaming peripherals category. Nulea's gaming peripherals lineup sits within the broader category mid-tier; price and specs are the deciding factors over brand loyalty here. Judge it on the specification table and the price rather than on sentiment: check the figures that decide your use case, then put it side-by-side with two or three close alternatives in the Compare tool before clicking through.

Common buyer scenarios for gaming peripherals of this kind: matching it to an existing build, replacing a failing part, or upgrading from a previous-generation equivalent. Check the spec table below against your current setup — particularly socket / form-factor / power-rating fields — and confirm compatibility on the retailer's listing before purchase. Prices and stock are set by the retailer and may have moved since this page was last updated.

Frequently Asked Questions

Does the Nulea M504 work with a Mac?

Yes, it is listed as compatible with Mac alongside Laptop, PC, and Desktop, and needs no drivers. Note that the forward and backward thumb buttons are not compatible with Mac OS.

What DPI settings does this mouse have?

Four: 800, 1200, 2400, and 3200 DPI. You cycle between them with the onboard DPI button, so you can drop to 800 for diagram editing and jump to 3200 for fast cursor travel.

Can I remap or program the buttons?

No. Nulea states all buttons on the M504 are non-programmable, so there is no software for macros or custom bindings. The forward and backward buttons work as-is on Windows.

How long is the cable, and does it need batteries?

It is a wired mouse with a 1.8m (about 5.9 ft) cable and a USB 2.0 connector, so there are no batteries to charge or replace and no dongle to lose.

Is a vertical mouse hard to get used to?

Nulea notes it may take a few days to adapt coming from a traditional flat mouse, since the 57-degree grip changes how your hand sits.

Can I turn the RGB lighting off or change it?

The M504 has 11 RGB lighting modes outlining the mouse, and the underglow is user-adjustable so you can pick the mode that suits your desk setup.

Key Features

  • Advanced Ergonomic Design: Designed as 57 degree natural grip and keep your forearm muscle under natural position, making movement smoother and more flexible, reducing arm discomfort and effectively relieving wrist pain. Compared with traditional mouse, with unique ergonomic vertical mouse design, it may take a few days to get used to using it.
  • 4 Adjustable DPI: Switch between DPI levels 800, 1200, 2400 and 3200 to adjust mouse responsiveness depending on your need and preference. Such as browsing the website, editing a diagram, drawing a picture, etc.
  • Plug and Play: The computer mouse no drivers required, plug and play wired mouse with 1.8m cable and USB 2.0 interface, easily accessible with standard setup features. Portable and lightweight, very easy to carry and store. The lightweight design of the mouse helps to improve posture, reduce pressure on wrists and muscles, and bring you a more comfortable office experience.
  • 11 RGB Lighting: The ergonomic mouse features RGB lighting that illuminates the outline of the mouse. Users can adjust the underglow depending on their preference to add a different working experience.
  • Featured Buttons: All buttons are easy to operate and won't twist your fingers. The Forward and Backward buttons are in an exact place and will help you greatly improve your efficiency. The button power is light and easy to click. Plus, metal non-slip scroll offers great durable quality. Note: Forward and Backward buttons are not compatible with MAC OS. All the buttons are non-programmable.

Full Specifications

BrandNulea
ColorB-Black
ThemeErgonomics
FinishMatte
Model NameM504
Style NameModern
Unit Count1.0 Count
ConnectivityUSB
Power SourceWired
CompatibilityPC, Switch, Mac
Button Quantity6
Connection TypeWired
Special FeatureErgonomic Design, LED Lights, Lightweight
Antenna LocationGaming
Hand OrientationRight
Hardware PlatformGeneric USB
Compatible DevicesLaptop, Personal Computer
Enclosure MaterialPlastic
Movement DetectionOptical
Additional FeaturesErgonomic Design, LED Lights, Lightweight
Full listing titleNulea M504 Wired Vertical Mouse, USB Optical Ergonomic Mouse Wired with 4 Adjustable DPI, 11 RGB Backlight Modes, Compatible for Laptop, PC, Desktop, Mac, Black

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Nulea M504 Wired Vertical Mouse, USB Optical Ergonomic Mouse Wired with 4 Adjustable DPI, 11 RGB Backlight Modes, Compatible for Laptop, PC, Desktop, Mac, Black is listed on Amazon. Price, availability, shipping and returns are set by Amazon and its sellers — check the listing for current terms. SpecPicks earns a small commission on qualifying purchases — thank you for supporting independent review work.

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Nulea M504 Wired Vertical Mouse, USB Optical Ergonomic Mouse Wired with 4 Adjustable DPI, 11 RGB Backlight Modes, Compatible for Laptop, PC, Desktop, Mac, Black
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