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Perixx PERIMICE-508II Wired Vertical Ergonomic Mouse - 6 Buttons, Adjustable DPI 1000/1600/3200/6400, Optical Sensor, USB Plug and Play, Right-Handed, Black
Perixx

Perixx PERIMICE-508II Wired Vertical Ergonomic Mouse

Bottom line: The Perixx PERIMICE-508II Wired Vertical Ergonomic Mouse: Vertical handshake shape cuts wrist twist during long sessions; main trade-off: right-handed only, no left-handed version of this model.

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Mike Perry — Hardware researcher since 2014. For retro PC hardware and period-correct parts, synthesises manufacturer documentation, community compatibility lists and marketplace listings rather than first-hand lab testing. Core beat: GPU performance across gaming, rendering, and local-LLM inference.

Pros & Cons

Pros

  • ✓ Vertical handshake shape cuts wrist twist during long sessions
  • ✓ Four DPI steps: 1000, 1600, 3200, 6400 via dedicated button
  • ✓ DPI setting survives unplugging and reboots via onboard memory
  • ✓ Forward/back thumb buttons in a 6-button layout
  • ✓ Switches rated for 3 million clicks

Cons

  • ✗ Right-handed only, no left-handed version of this model
  • ✗ Sized for small to medium hands, not large palms
  • ✗ Wired USB only, no Bluetooth or wireless receiver
  • ✗ Driver-free support listed for Windows 7 and up only

Manufacturer description

The Perixx PERIMICE-508II is a wired vertical ergonomic mouse built around a handshake grip that keeps your wrist from twisting through long document and browser sessions. A dedicated DPI button cycles through 1000, 1600, 3200, and 6400 DPI, and the built-in memory holds your chosen setting after you unplug the mouse or restart the machine, so you are not re-selecting sensitivity every morning. Connection is USB 2.0 plug and play with no driver install, and Perixx lists compatibility with Windows 7 and above. The 6-button layout adds forward and back thumb buttons to the usual left click…

SpecPicks Verdict

SpecPicks scored Perixx PERIMICE-508II Wired Vertical Ergonomic Mouse using a rating × review-volume × price-fit model applied to published specs and reviews across the keyboards & mice category. Perixx's keyboards & mice lineup sits within the broader category mid-tier; price and specs are the deciding factors over brand loyalty here. Judge it on the specification table and the price rather than on sentiment: check the figures that decide your use case, then put it side-by-side with two or three close alternatives in the Compare tool before clicking through.

Common buyer scenarios for keyboards & mice of this kind: matching it to an existing build, replacing a failing part, or upgrading from a previous-generation equivalent. Check the spec table below against your current setup — particularly socket / form-factor / power-rating fields — and confirm compatibility on the retailer's listing before purchase. Prices and stock are set by the retailer and may have moved since this page was last updated.

Frequently Asked Questions

Does the Perixx PERIMICE-508II work for left-handed users?

No. Perixx lists this model as right-handed only, and the vertical shell is molded for a right-hand grip.

What DPI settings does it support?

Four: 1000, 1600, 3200, and 6400 DPI, cycled with a dedicated DPI button. The mouse stores your last selection in built-in memory.

Do I need to install drivers?

No. It is a plug-and-play USB 2.0 mouse, and Perixx lists compatibility with Windows 7 and above with no driver required.

Will it fit large hands?

Perixx describes the design as suited to small to medium hand sizes, so measure your hand before ordering if you have a large palm.

Key Features

  • REDUCE HAND STRAIN WITH VERTICAL DESIGN – Ergonomic vertical shape promotes a natural handshake position, minimizing wrist twist to alleviate discomfort and fatigue—ideal for extended office tasks.
  • ADJUSTABLE DPI FOR CUSTOMIZED PRECISION – Easily switch between 1000, 1600, 3200, and 6400 DPI with a dedicated button. Built-in memory retains your preferred setting even after unplugging or restarting.
  • SIMPLE PLUG-AND-PLAY CONNECTION – Wired USB 2.0 interface delivers reliable, lag-free performance. Compatible with Windows 7 and above—no drivers required.
  • EFFICIENT 6-BUTTON FUNCTIONALITY – Includes standard left/right click, scroll wheel, and forward/backward navigation buttons to streamline browsing and document navigation.
  • DURABLE DESIGN FOR DAILY USE – Constructed with robust ABS material and rated for 3 million clicks. Lightweight, right-handed design suited for small to medium hand sizes.

Full Specifications

BrandPerixx
ColorBlack
Range10.0 meters
FinishMatte
Model NamePERIMICE-508 II
Style NameWired
Unit Count1.0 Count
ConnectivityUSB
Model Number12414
Power SourceCorded Electric
CompatibilitySwitch
Built-In MediaMouse
Item Type NamePERIMICE-508
Button Quantity5
Connection TypeWired
Mfr Part Number12414
Special FeaturePortable, Soundless
Antenna LocationGaming, Office
Hand OrientationRight
Hardware PlatformLinux, Mac, PC
Full listing titlePerixx PERIMICE-508II Wired Vertical Ergonomic Mouse - 6 Buttons, Adjustable DPI 1000/1600/3200/6400, Optical Sensor, USB Plug and Play, Right-Handed, Black

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Perixx PERIMICE-508II Wired Vertical Ergonomic Mouse - 6 Buttons, Adjustable DPI 1000/1600/3200/6400, Optical Sensor, USB Plug and Play, Right-Handed, Black is listed on Amazon. Price, availability, shipping and returns are set by Amazon and its sellers — check the listing for current terms. SpecPicks earns a small commission on qualifying purchases — thank you for supporting independent review work.

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