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Evoluent – Inventor of The Vertical Mouse – VM4S Ergonomic Vertical Mouse Right Hand Small Wired USB, Sculpted for Comfort, Reduces Wrist Strain, 4 Speeds, 6 Customizable Buttons in Windows
Evoluent

Evoluent – Inventor of The Vertical Mouse – VM4S Ergonomic Vertical Mouse Right Hand Small Wired USB, Sculpted for Comfort, Reduces Wrist Strain, 4 Speeds, 6 Customizable Buttons in Windows

Bottom line: The Evoluent – Inventor of The Vertical Mouse – VM4S Ergonomic Vertical ($89.95 on Amazon as of 2026-10-06): Neutral handshake grip cuts forearm twisting versus a flat mouse; main trade-off: small size fits smaller right hands only; larger hands need the full-size VM4.

$89.95

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Buy on Amazon — $89.95 Compare to similar gaming peripherals

By , Founder & Editor-in-Chief · Listing data updated

Mike Perry — Hardware researcher since 2014. For keyboards, mice, headsets and other PC peripherals, synthesises manufacturer specs and independent reviews rather than first-hand lab testing. Core beat: GPU performance across gaming, rendering, and local-LLM inference.

*Price sourced from Amazon.com. Last updated 2026-10-06. Price and availability subject to change.

Pros & Cons

Pros

  • ✓ Neutral handshake grip cuts forearm twisting versus a flat mouse
  • ✓ Pinky support ledge stops your little finger dragging on the desk
  • ✓ 4 pointer-speed levels switch from top buttons with indicator lights
  • ✓ 6 buttons plus wheel remap freely via Evoluent Mouse Manager on Windows

Cons

  • ✗ Small size fits smaller right hands only; larger hands need the full-size VM4
  • ✗ Right-hand build only, so left-handed users must look elsewhere
  • ✗ USB wired, no wireless or Bluetooth option on this model
  • ✗ Button remapping software is Windows-only; Mac and Linux get default functions

Manufacturer description

The Evoluent VM4S is the small right-hand model of the vertical mouse Jack Lo invented in 1994 and first shipped commercially in 2002, and it holds your hand in a neutral handshake position so your forearm stays untwisted through a full workday. That posture is the whole point: less forearm rotation, less wrist strain, and a pinky support ledge that keeps your little finger from dragging across the desk. Sizing matters more on a vertical mouse than a conventional one, and the S body is built for smaller right hands rather than being a shrunken afterthought. Four pointer-speed levels switch…

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SpecPicks Verdict

SpecPicks scored Evoluent – Inventor of The Vertical Mouse – VM4S Ergonomic Vertical… using a rating × review-volume × price-fit model applied to published specs and reviews across the gaming peripherals category. Evoluent's gaming peripherals lineup sits within the broader category mid-tier; price and specs are the deciding factors over brand loyalty here. Judge it on the specification table and the price rather than on sentiment: check the figures that decide your use case, then put it side-by-side with two or three close alternatives in the Compare tool before clicking through.

Common buyer scenarios for gaming peripherals of this kind: matching it to an existing build, replacing a failing part, or upgrading from a previous-generation equivalent. Check the spec table below against your current setup — particularly socket / form-factor / power-rating fields — and confirm compatibility on the retailer's listing before purchase. Prices and stock are set by the retailer and may have moved since this page was last updated.

Frequently Asked Questions

Will the VM4S fit my hand, or should I get the larger model?

The VM4S is the small right-hand version. Evoluent also makes a regular-size VM4 body, so measure your hand against the listing dimensions before ordering; the small shell is meant for smaller right hands rather than a universal fit.

Does this mouse work on a Mac or a Linux machine?

Yes for basic use. It is USB plug-and-play with any USB-compatible system that supports mouse input. The Evoluent Mouse Manager customization software is Windows-only, so on other systems the six buttons use their default assignments.

How do I change the pointer speed?

Four pointer-speed levels are built into the mouse itself and switch using top-mounted buttons, with indicator lights showing the active level. No driver install or operating-system settings change is needed.

Is this mouse wireless?

No. The VM4S is USB wired. Evoluent sells wireless models separately, but this SKU is the wired version, so it draws power from the USB port and never needs charging or batteries.

What can the six buttons actually be programmed to do?

With the optional Evoluent Mouse Manager on Windows, button and wheel functions are almost fully customizable, including collapsing repeated hand movements into single clicks and controlling screen brightness.

Key Features

  • The Vertical Mouse was invented by Jack Lo in 1994. Jack founded Evoluent and introduced the world’s first Vertical Mouse product in 2002, marking a significant advance in computer ergonomics.
  • The Evoluent Vertical Mouse supports your hand in a neutral handshake position that reduces forearm twisting and wrist strain. This design has been validated by decades of highly positive user feedback to Evoluent, and the wide adoption of the technology across the mouse industry by the 2020s.
  • Evoluent’s Vertical Mouse remains a standout choice as a thoughtfully designed, precision product that offers unparalleled comfort, user-friendliness and functionality, backed by over 30 years of Vertical Mouse expertise of its designer.
  • 4 levels of pointer speeds adjustable with top-mounted buttons and indicator lights. Plug-n-play with any USB-compatible system that supports mouse input.
  • Optional Evoluent Mouse Manager software for Windows offers nearly unlimited customization of button and wheel functions to reduce many hand movements to simple clicks, control your screen brightness, and more.
  • Precision sensor tracks mouse movement accurately and reliably on a wide variety of surfaces. High quality materials and workmanship.

Full Specifications

BrandEvoluent
ColorBlack, purple
Range5.0 meters
ThemeGame of Thrones
FinishGlossy
PatternSingle
Model NameEvoluent Vertical Mouse 4 Small Right Hand Wired Ergonomic Mouse
Style NameWired
Unit Count2.6 Pounds
ConnectivityUSB
Model NumberVM4S
Power SourceWired USB
Built-In MediaMaus
Item Type NameBgears Long life 2 Ball bearing Fan High performance specification 120 mm fan (thickness 38 mm)
Button Quantity6
Connection TypeWired
Mfr Part NumberVM4R
Special FeatureErgonomic Design
Antenna LocationOffice
Hand OrientationRight

Ready to buy?

Evoluent – Inventor of The Vertical Mouse – VM4S Ergonomic Vertical Mouse Right Hand Small Wired USB, Sculpted for Comfort, Reduces Wrist Strain, 4 Speeds, 6 Customizable Buttons in Windows is listed on Amazon. Price, availability, shipping and returns are set by Amazon and its sellers — check the listing for current terms. SpecPicks earns a small commission on qualifying purchases — thank you for supporting independent review work.

Buy on Amazon — $89.95

*Price sourced from Amazon.com. Last updated 2026-10-06. Price and availability subject to change.

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Evoluent – Inventor of The Vertical Mouse – VM4S Ergonomic Vertical Mouse Right Hand Small Wired USB, Sculpted for Comfort, Reduces Wrist Strain, 4 Speeds, 6 Customizable Buttons in Windows
$89.95
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