Synology DiskStation DS1621+ NAS Server with Ryzen 2.2GHz CPU
Bottom line: The Synology DiskStation DS1621+ NAS Server with Ryzen 2.2GHz CPU is a specs-and-price decision rather than a crowd-consensus one in the external storage category, priced around $4699.00 on Amazon as of 2026-10-07. Check the specification table below against one or two close alternatives — on price and spec fit, not on star ratings.
As an Amazon Associate, SpecPicks earns from qualifying purchases. Full disclosure →
*Price sourced from Amazon.com. Last updated 2026-10-07. Price and availability subject to change.
Pros & Cons
Pros
- ✓ Synology NAS chassis comes in a sealed box.
- ✓ Backed by Synology's warranty and support channels
Cons
- ✗ Check the listed dimensions, connectors and platform compatibility against your setup before ordering
- ✗ Price, stock, shipping and returns are set by the retailer and may have changed since this page was last updated
Manufacturer description
Synology DiskStation DS1621+ made for a large assortment of server functions, such as iSCSI targets backup, file storage, email servers, & domain controllers.Form Factor: NAS Tower ServerInternal File System Format: EXT4, BtrfsPorts: 4 x RJ-45 1GbE LAN Ports (with Link Aggregation/ Failover support); 3 x USB 3.2 Ports; 2 x eSATA Ports; Btrfs File System for Advanced LUN iSCSI ServiceProcessor: Ryzen V1500B 4-Core 2.2GHz CPUMemory: 32GB DDR4 ECC SODIMM MemoryStorage: 60TB (6 x 10TB) SATA HDDs for High-Capacity StoragePower: Single Power SupplyOperating System: Synology DSM SoftwareIdeal for…
SpecPicks Verdict
SpecPicks scored Synology DiskStation DS1621+ NAS Server with Ryzen 2.2GHz CPU using a rating × review-volume × price-fit model applied to published specs and reviews across the external storage category. Synology's external storage lineup sits within the broader category mid-tier; price and specs are the deciding factors over brand loyalty here. Judge it on the specification table and the price rather than on sentiment: check the figures that decide your use case, then put it side-by-side with two or three close alternatives in the Compare tool before clicking through.
Common buyer scenarios for external storage of this kind: matching it to an existing build, replacing a failing part, or upgrading from a previous-generation equivalent. Check the spec table below against your current setup — particularly socket / form-factor / power-rating fields — and confirm compatibility on the retailer's listing before purchase. Prices and stock are set by the retailer and may have moved since this page was last updated.
Key Features
- Synology DiskStation DS1621+, made for a variety of server roles, such as iSCSI targets backup, large file storage, email servers, and domain controllers. Powerful, high-capacity, scalable storage that fits in any environment. A powerhouse capable of fitting into small and medium business environments with intensive, multi-user workloads.
- Ryzen V1500B Quad-Core 2.2GHz CPU; 32GB DDR4 ECC SODIMM Memory; M.2 Storage: 1TB (2 x 500GB) M.2 Solid State Drives for Ultra-Fast Storage; File Storage: 60TB (6 x 10TB) SATA HDDs for High-Capacity Storage; 4 x RJ-45 1GbE LAN Ports (with Link Aggregation / Failover support); 3 x USB 3.2 Ports; 2 x eSATA Ports
- Features: iSCSI Target Protocol, Cache Acceleration, Virtual Machine Manager, Synology High Availability, Synology MailPlus, Central Management System, Security Advisor, AES 256-bit Encryption, 2 Factor Authentication, Cloud Station Suite, 4K Multimedia Server role, Active Backup for VMware and Windows, Synology Drive, Active Backup for Office 365 and G Suite, Surveillance Station role, Collaboration Suite, and many more
- Synology NAS chassis comes in a sealed box.
- Hard drives and memory upgrades included separately, NOT installed, installation required.
Full Specifications
| Brand | Synology |
|---|---|
| Color | Black |
| Material | Metal |
| Unit Count | 1 Count |
| Connectivity | USB |
| Mounting Type | Rack Mount |
| Storage Volume | 60 TB |
| Compatible Devices | Server |
| Enclosure Material | Metal |
| Warranty Description | Description |
| Full listing title | Synology DiskStation DS1621+ NAS Server with Ryzen 2.2GHz CPU, 32GB Memory, 60TB HDD Storage, 1TB M.2 NVMe SSD, 4 x 1GbE LAN Ports, DSM Operating System |
Ready to buy?
Synology DiskStation DS1621+ NAS Server with Ryzen 2.2GHz CPU, 32GB Memory, 60TB HDD Storage, 1TB M.2 NVMe SSD, 4 x 1GbE LAN Ports, DSM Operating System is listed on Amazon. Price, availability, shipping and returns are set by Amazon and its sellers — check the listing for current terms. SpecPicks earns a small commission on qualifying purchases — thank you for supporting independent review work.
*Price sourced from Amazon.com. Last updated 2026-10-07. Price and availability subject to change.
Related External Storage
More guides & deep dives from the SpecPicks archive
Browse all articles & guides →- Emulation Hardware in 2026: FPGA, Software, and Cart-Reader Ecosystems
- Best Budget Gaming PC Build 2026 — ~$1,000 ($800 on Sale)
- The Complete Voodoo5 5500 AGP Driver Guide (2026 Edition)
- How to Build a Windows 98 Retro PC in 2026
- RTX 4070 Super vs RX 7800 XT — Which to Buy in 2026
- Best Retro Handhelds in 2026 — From $35 to $500
- Best 1440p Gaming GPUs in 2026
More reviews from the SpecPicks archive
Browse all reviews →- RTX 5090 vs RTX 5070: Specs, Value & Which to Buy
- Best CPU for Gaming 2026: Price-to-Performance Guide
- Best Gaming Monitor for Console and PC Crossover (2026)
- MAYFLASH F300 vs GameSir G7 SE: Best Controller for PC Fighting Games (2026)
- Sound Blaster Audigy FX vs Sound BlasterX G6 for Retro Win98/XP Builds
- Best Wireless Streaming Microphones for Twitch in 2026
- Retro Console Mods in Canada: 2026 Legal & Hardware Guide
- Headset Mic vs USB Mic for Discord and Twitch: Recon 50 vs Blue Yeti
- xAI Open-Sources Grok-Build: Running Agentic Coding on Your Own GPU
- Best GPU Upgrade From a GTX 1050 Ti for Local LLMs in 2026
- Best SSD for PS4 Pro: SATA Upgrades That Actually Help
- Wired Headset vs Bluetooth Earbuds for Competitive FPS: The Latency Math
- ASRock Phantom Gaming vs Steel Legend 360 LCD Review
- Unified RAM for LLMs: 2025-2026 Hardware Guide
- Putting a Modern SATA SSD in a Win98/XP Retro Build via an IDE Bridge
- Best Uses for Old RAM Sticks in 2025
- Best Gaming Mouse Pad for Esports FPS in 2026
- Dual RTX 3090 PC Builds: PSU, Cooling, and Cost in 2025
- Aider vs Cline vs Cursor for Local Coding on a 12GB GPU (2026)
- RTX 5090 AI Build Guide: CPU, RAM, PSU & Cooling for Local Inference
- Best Raspberry Pi Alternative for Klipper (2025 Guide)
- Best Webcam for Twitch Streaming Under $100 in 2026
- 3dfx Voodoo2 SLI in 2026: Building a Period-Correct Windows 98 Glide Rig
- Logitech G502 Hero vs MK270 Combo: Best PC Setup for Sub-$50
Earliest SpecPicks reviews
Browse full archive →- Best GPU for Llama 3.1 8B (2026)
- Best GPU for Qwen 3 14B (2026)
- Best GPU for Qwen 3 32B (2026)
- Best GPU for Llama 3.1 70B (2026)
- Best GPU for DeepSeek-R1 32B (2026)
- Best GPU for Llama 3.1 405B (2026)
- How to run Llama 3.1 8B on NVIDIA GeForce RTX 5090
- How to run Qwen 3 14B on NVIDIA GeForce RTX 5090
- How to run Qwen 3 32B on NVIDIA GeForce RTX 5090
- How to run Llama 3.1 70B on NVIDIA GeForce RTX 5090
- How to run DeepSeek-R1 32B on NVIDIA GeForce RTX 5090
- How to run Llama 3.1 8B on NVIDIA GeForce RTX 4090