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Evoluent – Inventor of the Vertical Mouse – VM4RW Ergonomic Vertical Mouse Right Hand Regular Size Wireless USB, Sculpted for Comfort, Reduces Wrist Strain, 4 Speeds, 6 Customizable Buttons in Windows
Evoluent

Evoluent – Inventor of the Vertical Mouse – VM4RW Ergonomic Vertical Mouse Right Hand Regular Size Wireless USB, Sculpted for Comfort, Reduces Wrist Strain, 4 Speeds, 6 Customizable Buttons in Windows

Bottom line: The Evoluent – Inventor of the Vertical Mouse – VM4RW Ergonomic Vertical ($109.45 on Amazon as of 2026-10-06): Upright neutral hand position avoids the forearm twist a flat mouse forces; main trade-off: right-hand, regular-size only; no left-hand or alternate size in this listing.

$109.45

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Buy on Amazon — $109.45 Compare to similar gaming peripherals

By , Founder & Editor-in-Chief · Listing data updated

Mike Perry — Hardware researcher since 2014. For keyboards, mice, headsets and other PC peripherals, synthesises manufacturer specs and independent reviews rather than first-hand lab testing. Core beat: GPU performance across gaming, rendering, and local-LLM inference.

*Price sourced from Amazon.com. Last updated 2026-10-06. Price and availability subject to change.

Pros & Cons

Pros

  • ✓ Upright neutral hand position avoids the forearm twist a flat mouse forces
  • ✓ Six buttons, including two thumb buttons, remap via Evoluent Mouse Manager
  • ✓ Four pointer-speed steps switch from a side control without releasing your grip
  • ✓ Extra-wide bottom lip keeps your last finger from rubbing the desk

Cons

  • ✗ Right-hand, regular-size only; no left-hand or alternate size in this listing
  • ✗ Full six-button customization is specified for Windows, not macOS or Linux
  • ✗ Button remapping requires installing the Evoluent Mouse Manager driver
  • ✗ Listing pairs wireless USB with a USB wired connection; confirm before buying

Manufacturer description

The Evoluent VM4RW VerticalMouse 4 comes from the company that invented the vertical mouse, and the shape shows it. Instead of forcing your forearm to twist flat against the desk, the sculpted body holds your hand in an upright, neutral handshake position that Evoluent designed to reduce wrist strain over long sessions. Six buttons are programmable through the included Evoluent Mouse Manager software, including a second thumb button added on this generation, so you can map per-application shortcuts without contorting your fingers to reach them. Pointer speed steps through four settings, low…

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SpecPicks Verdict

SpecPicks scored Evoluent – Inventor of the Vertical Mouse – VM4RW Ergonomic Vertical… using a rating × review-volume × price-fit model applied to published specs and reviews across the gaming peripherals category. Evoluent's gaming peripherals lineup sits within the broader category mid-tier; price and specs are the deciding factors over brand loyalty here. Judge it on the specification table and the price rather than on sentiment: check the figures that decide your use case, then put it side-by-side with two or three close alternatives in the Compare tool before clicking through.

Common buyer scenarios for gaming peripherals of this kind: matching it to an existing build, replacing a failing part, or upgrading from a previous-generation equivalent. Check the spec table below against your current setup — particularly socket / form-factor / power-rating fields — and confirm compatibility on the retailer's listing before purchase. Prices and stock are set by the retailer and may have moved since this page was last updated.

Frequently Asked Questions

Is the Evoluent VM4RW available for left-handed users?

No. The VM4RW is the right-hand, regular-size VerticalMouse 4. Check the Evoluent product listing for a left-hand version.

Is the VM4RW wireless or wired?

The product title lists it as wireless USB, while the compatibility feature also references a reliable USB wired connection. Confirm the connection type on the listing before ordering.

How many buttons can I customize, and do I need software?

Six buttons, including two thumb buttons, are customizable using the included Evoluent Mouse Manager software. Evoluent specifies customization in Microsoft Windows.

Does it work with Mac and Linux?

Evoluent lists the mouse as compatible with Microsoft Windows, Mac OS and Linux. The six-button customization is stated for Windows.

Key Features

  • Ergonomic Design for Wrist Comfort – The Evoluent VM4RW Vertical Mouse 4 gently supports your hand in an upright neutral position, reducing strain and alleviating wrist discomfort. Perfect for those seeking an ergonomic mouse for carpal tunnel issues.
  • Programmable Buttons for Personalized Use – Easily customize button functions using the included Evoluent Mouse Manager software. Adapt your wireless Vertical Mouse settings to different programs for ultimate efficiency and versatility.
  • Adjustable Pointer Speed – Effortlessly control your cursor with speed settings ranging from low to high using the controls on the side. No need to release your grip to adjust, making this vertical ergonomic mouse a gamer’s favorite.
  • Designed for Comfort – Featuring a broad bottom lip for enhanced comfort, this upright mouse delivers support during prolonged use. Ideal for office work, gaming, and other computer tasks requiring precision.
  • Wide Compatibility - This ergonomic wireless mouse works seamlessly with Microsoft Windows, Mac OS, and Linux systems. A reliable USB wired connection ensures consistent performance for both office professionals and gamers.

Full Specifications

BrandEvoluent
ColorMetallic Blue & Black - Wireless
Range5.0 meters
FinishGlossy
PatternSingle
Model NameEvoluent Vertical Mouse 4 Right Hand USB Wireless
Style NameRight Hand
Unit Count1.0 Count
ConnectivityWireless, USB
Model NumberVM4RW
Power SourceAA battery
CompatibilityMac, Linux
Item Type NameGray Star TRIBE DC Comic Catwoman USB Flash Memory Drive DC comics Cat Woman FD031404
Button Quantity6
Connection TypeWired
Mfr Part Number2
Special FeatureErgonomic Design
Antenna LocationIndoor
Hand OrientationRight
Hardware PlatformPC, Mac, Linux

Ready to buy?

Evoluent – Inventor of the Vertical Mouse – VM4RW Ergonomic Vertical Mouse Right Hand Regular Size Wireless USB, Sculpted for Comfort, Reduces Wrist Strain, 4 Speeds, 6 Customizable Buttons in Windows is listed on Amazon. Price, availability, shipping and returns are set by Amazon and its sellers — check the listing for current terms. SpecPicks earns a small commission on qualifying purchases — thank you for supporting independent review work.

Buy on Amazon — $109.45

*Price sourced from Amazon.com. Last updated 2026-10-06. Price and availability subject to change.

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Evoluent – Inventor of the Vertical Mouse – VM4RW Ergonomic Vertical Mouse Right Hand Regular Size Wireless USB, Sculpted for Comfort, Reduces Wrist Strain, 4 Speeds, 6 Customizable Buttons in Windows
$109.45
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